The Gorge Strangelet Quest is the final Strangelet quest you'll need to complete in The Edge of Fate, after completing the three prior Strangelet Quests. This quest contains the missions Calculus, Distruption, and Quarantine, and gives you access to the next upgrade for your Matterspark ability.
This mission takes place in the Gorge region of Kepler, in which you'll work closely alongside Orin, Ikora and Lodi to discover more about the Choral Vex and try to get ahead of the Conductor's plans, to be able to stop her from wreaking havoc on the world of the Aionians.
Quest Guide
1. Find and speak with Orin in the Gorge.

To progress with this quest, you'll have to enter the Gorge and find Orin. To unlock the Gorge, set a waypoint towards it on the map, and interact with the terminal to unlock the barrier.

Continue forward to find Orin.
2. Acquire Accelerons to gain access to Missions
Here, to progress this quest, you'll need to complete two Encounters within Kepler: Surveillance and Siphon, to acquire two Accelerons. Each Acceleron will give you access to a mini-mission: Calculus and Disruption. You'll need to complete both missions to progress this quest.
You can find our guides to the both of the missions at the link below:
Acceleron: Surveillance
After speaking to Orin, turn around and continue through the Gorge, using Mattermorph to guide your way through the traps.

As you progress, you'll enter a space with Vex Laser traps across the floor. Be careful in this area, as stepping inside of these will activate the alarms and cause more Choral Vex to appear.

To disable these, kill all Hobgoblin Shield-Casters inside the room. This will expose a signal cube at the top of the room. Break it to deactivate the mechanism.

In the next area, there will be two signal cubes to break to deactivate the traps. Kill all Hobgoblin Shield-Casters in the area to expose the signal cubes and disable the traps.

Use Matterspark to continue forward to the final encounter room, where you'll find a large Hydra hidden inside of a shield.

There will be three signal cubes holding this shield together. Eliminate all Hobgoblin Shield-Casters to expose the signal cubes and reveal the 'Sentinel of the Conductor'. Begin damaging the boss.

Once at half health, the Hydra will retreat into its shield again, and you'll have to destroy more Hobgoblins to bring down the shield.

Once down, defeat the boss to claim your rewards, and acquire Acceleron, Surveillance. This will unlock access to the mission Disruption, which you can choose to complete now, or retrieve the next Acceleron before completing both missions. The Disruption mission can be found in the center of the Gorge, close to where you spoke to Orin at the beginning of the quest.
To learn how to solve the Disruption mission, read our guide below.
Acceleron: Siphon
After speaking to Orin, turn around and continue through the Gorge, navigating through the rocky terrain until you enter the Stellar Sink.

Continue forward, following the trail of Choral Vex and 'Coryphaeus Hydras', slaying out as you go.

To progress past this room, you'll have to use Matterspark to it's full potential.

Enter the pillar inside the middle to acquire your next upgrade, Matterspark II.

With Matterspark II, you'll now be able to supercharge your Matterspark ability, and send out a burst attack of Arc energy by using your Super key. The charge meter is located on the left of your HUD, above your weapons.
To supercharge Matterspark, move around or damage enemies whilst in Matterspark mode. By picking up the small orbs of Arc energy located around the room, you can quickly supercharge Matterspark.

To progress through this encounter, use your supercharge attack on the Matterspark-baned Vex. Clear the room of enemies to lower the barrier and continue forward.

Weave your way around the laser walls to enter the final encounter.

To complete this encounter, you'll have to defeat the Minotaur boss 'Meridi and Didyo, The Assimilating Minds'. You'll use both Mattermorph and your new supercharged Matterspark abilties to clear the encounter.

You'll need to find the source of the Boss's shield. Head past the boss into the second doorway, clearing waves of enemies as you do.

At the back of the room, you'll find a shielded signal cube and two Hobgoblins. Eliminate the Hobgoblins to expose the signal cube, and destroy it.

Once destroyed, you can enter Matterspark and go through the tunnel to enter the boss room again, and begin damage.

Once the boss is at half health, its shield will appear once more. First, enter Matterspark and use your supercharge ability to clear the room of Matterspark-baned Vex.

Once the room is cleared, look upwards to find two Hobgoblins guarding a small room. Eliminate the Hobgoblins and head inside.

Here, you'll find a Mattermorph pillar. Gain Mattermorph and head back outside towards the laser door.

Use your Mattermorph on the wall to the left of the laser door to create an entrance up to the top.

Head through and repeat the steps from last time, slaying out enemies and killing Hobgoblins to expose the Boss's shield. Enter the arena once more and eliminate the Minotaur.

Once the boss has been defeated, you'll find your rewards in the middle, and claim Acceleron Siphon. This will unlock access to the mission Calculus, which you can choose to complete now, or claim the other Acceleron before completing both missions. The Calculus mission can be found in the center of the Gorge, close to where you spoke to Orin at the beginning of the quest.
To learn how to solve the Calculus mission, read our guide in the link below.
3. Defeat the Vex Mind and retrieve the Strangelet Capsule
After completing both Mission Calculus and Disruptuon, you'll have to complete the Quarantine mission. This mission will grant you the last remaining Strangelet Capsule, and marks the end of The Gorge Strangelet quest.
Read our guide in the link below on how to solve the Quarantine mission: